Oxidative stress which caused by increasing of free radical ROS/RNS in the organs of Corti, causing apoptosis and necrosis of cochlear hair cell. Medical Faculty of General Achmad Yani UniversityĪcoustic trauma, Ebselen, GPx, MDA, Otoacoustic emission, AbstractĮxcessive noise exposure may cause mechanical and metabolic (oxidative stress) to the inner ear structure (cochlea), resulting in acoustic trauma (TA).
